Differential Effect of Solution Conditions on the Conformation of the Actinoporins Sticholysin II and Equinatoxin II

Actinoporins are a family of pore-forming proteins with hemolytic activity. The structural basis for such activity appears to depend on their correct folding. Such folding encompasses a phosphocholine binding site, a tryptophan-rich region and the activity-related N-terminus segment. Additionally, d...

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Bibliographic Details
Main Authors: EDSON V.F. FAUTH, EDUARDO M. CILLI, RODRIGO LIGABUE-BRAUN, HUGO VERLI
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2014-12-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401949&lng=en&tlng=en