Exacerbation of N-nitrosodiethylamine Induced Hepatotoxicity and DNA Damage in Mice Exposed to Chronic Unpredictable Stress

Exacerbation of N-nitrosodiethylamine Induced Hepatotoxicity and DNA Damage in Mice Exposed to Chronic Unpredictable Stress

Psychological stress contributes to increased susceptibility to a number of diseases including cancer. The present study was designed to assess the effect of chronic unpredictable stress on N-nitrosodiethylamine induced liver toxicity in terms of in vivo antioxidant status and DNA damage in Swiss al...

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Bibliographic Details
Main Authors: Nayeem Bilal, Nida Suhail, Shirin Hasan, Ghulam M. Ashraf, Sabiha Fatima, Husain Y. Khan, Mariam S. Alharbi, Athanasios Alexiou, Naheed Banu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
N-nitrosodiethylamine
chronic unpredictable stress
hepatotoxicity
DNA damage
carcinogenesis
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00360/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00360/full

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