HLA Does Not Impact on Short-Medium-Term Antibody Response to Preventive Anti-SARS-Cov-2 Vaccine

HLA Does Not Impact on Short-Medium-Term Antibody Response to Preventive Anti-SARS-Cov-2 Vaccine

The response to anti-SARS-Cov-2 preventive vaccine shows high interpersonal variability at short and medium term. One of the explanations might be the individual HLA allelic variants. Indeed, B cell response is stimulated and sustained by CD4+ T helper cells activated by antigens presented by HLA-cl...

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Bibliographic Details
Main Authors: Concetta Ragone, Serena Meola, Pasqualina C. Fiorillo, Roberta Penta, Laura Auriemma, Maria Lina Tornesello, Leonardo Miscio, Ernesta Cavalcanti, Gerardo Botti, Franco M. Buonaguro, Attilio Bianchi, Luigi Buonaguro, Maria Tagliamonte
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
HLA-DQ antigens
BNT162b2 mRNA COVID-19 vaccine
antibody titer level
HLA-DR antigens
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.734689/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.734689/full

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