GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals

GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals

The synaptic connection from medial habenula (MHb) to interpeduncular nucleus (IPN) is critical for emotion-related behaviors and uniquely expresses R-type Ca2+ channels (Cav2.3) and auxiliary GABAB receptor (GBR) subunits, the K+-channel tetramerization domain-containing proteins (KCTDs). Activatio...

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Bibliographic Details
Main Authors: Pradeep Bhandari, David Vandael, Diego Fernández-Fernández, Thorsten Fritzius, David Kleindienst, Cihan Önal, Jacqueline Montanaro, Martin Gassmann, Peter Jonas, Akos Kulik, Bernhard Bettler, Ryuichi Shigemoto, Peter Koppensteiner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
gabab receptor
Cav2.3
KCTD
r-type calcium channel
medial habenula
interpeduncular nucleus
Online Access:https://elifesciences.org/articles/68274

Internet

https://elifesciences.org/articles/68274

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