NR2F1 disrupts synergistic activation of the MTTP gene transcription by HNF-4α and HNF-1α

Regulation of microsomal triglyceride transfer protein (MTP) expression mainly occurs at the transcriptional level. We have previously shown that MTTP gene expression was repressed in nondifferentiated intestinal cells by nuclear receptor 2 family 1 (NR2F1). However, mechanisms involved in the repre...

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Bibliographic Details
Main Authors: Kezhi Dai, M. Mahmood Hussain
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520392208