Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma

Cell-free DNA and circulating TERT promoter mutation for disease monitoring in newly-diagnosed glioblastoma

Abstract The clinical implications of plasmatic cell-free and tumor DNA (cfDNA and ctDNA) are challenging in glioblastoma. This prospective study included 52 consecutive newly diagnosed glioblastoma (n = 49) or gliosarcoma (n = 3) patients treated with concomitant temozolomide and radiotherapy (RT-T...

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Bibliographic Details
Main Authors: Maxime Fontanilles, Florent Marguet, Ludivine Beaussire, Nicolas Magne, Louis-Ferdinand Pépin, Cristina Alexandru, Isabelle Tennevet, Chantal Hanzen, Olivier Langlois, Fabrice Jardin, Annie Laquerrière, Nasrin Sarafan-Vasseur, Fréderic Di Fiore, Florian Clatot
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Acta Neuropathologica Communications
Subjects:
Glioblastoma
Cell-free DNA
Circulating tumor DNA
TERT promoter mutation
Liquid biopsy
Online Access:http://link.springer.com/article/10.1186/s40478-020-01057-7

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http://link.springer.com/article/10.1186/s40478-020-01057-7

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