Molecular and Electrophysiological Role of Diabetes-Associated Circulating Inflammatory Factors in Cardiac Arrhythmia Remodeling in a Metabolic-Induced Model of Type 2 Diabetic Rat

Molecular and Electrophysiological Role of Diabetes-Associated Circulating Inflammatory Factors in Cardiac Arrhythmia Remodeling in a Metabolic-Induced Model of Type 2 Diabetic Rat

Background: Diabetic patients have prolonged cardiac repolarization and higher risk of arrhythmia. Besides, diabetes activates the innate immune system, resulting in higher levels of plasmatic cytokines, which are described to prolong ventricular repolarization. Methods: We characterize a metabolic...

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Bibliographic Details
Main Authors: Julian Zayas-Arrabal, Amaia Alquiza, Erkan Tuncay, Belma Turan, Monica Gallego, Oscar Casis
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
cytokines
arrhythmia
torsade de pointes
potassium current
insulin resistance
Online Access:https://www.mdpi.com/1422-0067/22/13/6827

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https://www.mdpi.com/1422-0067/22/13/6827

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