Nutraceutical Potential of Five Mexican Brown Seaweeds
In search of pharmaceutically active products to control type 2 diabetes, five brown seaweeds (Silvetia compressa, Cystoseira osmundacea, Ecklonia arborea, Pterygophora californica, and Egregia menziesii) from the Northwest Mexican Pacific coast were investigated. Proximate composition and total pol...
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Format: | Article |
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Hindawi Limited
2019-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2019/3795160 |
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Article |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ana Rocío Múzquiz de la Garza Mireya Tapia-Salazar Maribel Maldonado-Muñiz Julián de la Rosa-Millán Janet Alejandra Gutiérrez-Uribe Liliana Santos-Zea Bertha Alicia Barba-Dávila Denis Ricque-Marie Lucía Elizabeth Cruz-Suárez |
spellingShingle |
Ana Rocío Múzquiz de la Garza Mireya Tapia-Salazar Maribel Maldonado-Muñiz Julián de la Rosa-Millán Janet Alejandra Gutiérrez-Uribe Liliana Santos-Zea Bertha Alicia Barba-Dávila Denis Ricque-Marie Lucía Elizabeth Cruz-Suárez Nutraceutical Potential of Five Mexican Brown Seaweeds BioMed Research International |
author_facet |
Ana Rocío Múzquiz de la Garza Mireya Tapia-Salazar Maribel Maldonado-Muñiz Julián de la Rosa-Millán Janet Alejandra Gutiérrez-Uribe Liliana Santos-Zea Bertha Alicia Barba-Dávila Denis Ricque-Marie Lucía Elizabeth Cruz-Suárez |
author_sort |
Ana Rocío Múzquiz de la Garza |
title |
Nutraceutical Potential of Five Mexican Brown Seaweeds |
title_short |
Nutraceutical Potential of Five Mexican Brown Seaweeds |
title_full |
Nutraceutical Potential of Five Mexican Brown Seaweeds |
title_fullStr |
Nutraceutical Potential of Five Mexican Brown Seaweeds |
title_full_unstemmed |
Nutraceutical Potential of Five Mexican Brown Seaweeds |
title_sort |
nutraceutical potential of five mexican brown seaweeds |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2019-01-01 |
description |
In search of pharmaceutically active products to control type 2 diabetes, five brown seaweeds (Silvetia compressa, Cystoseira osmundacea, Ecklonia arborea, Pterygophora californica, and Egregia menziesii) from the Northwest Mexican Pacific coast were investigated. Proximate composition and total polyphenol content (TPC) as phloroglucinol equivalents (PGE) were determined for the five seaweed powders and their respective hydroethanolic (1 : 1) extracts. Extracts were screened for their radical scavenging activity (DPPH and ORAC) and glycosidase inhibitory activity. HPLC-DAD, HPLC-MS-TOF, and ATR-FT-IR methodologies were used to identify the most abundant phlorotannins and sulfated polysaccharides in the extracts. Hydroethanolic extracts contained minerals (17 to 59% of the dry matter), proteins (4 to 9%), ethanol-insoluble polysaccharides (5.4 to 53%), nitrogen-free extract (NFE) (24.4 to 70.1%), lipids (5 to 12%), and TPC (2.6 to 47.7 g PGE per 100 g dry extract). S. compressa and E. arborea dry extracts presented the lowest ash content (26 and 17%, respectively) and had some of the highest phenolic (47.7 and 15.2 g PGE per 100 g extract), NFE (57.3 and 70.1%), and soluble polysaccharide (19.7 and 53%) contents. S. compressa and E. arborea extracts had the highest antioxidant activity (IC50 DPPH 1.7 and 3.7 mg mL−1; ORAC 0.817 and 0.801 mmol Trolox equivalent/g extract) and the highest α-amylase and α-glucosidase inhibitory capacities (IC50 940 and 1152 μg mL−1 against α-amylase and 194 and 647 μg mL−1 against α-glucosidase). The most abundant phlorotannins identified in the extracts were phloretol, fucophloroethol, and two- and three-phloroglucinol unit (PGU) phlorotannins. Laminarin, fucoidan, and alginate were among the sulfated polysaccharides identified in the extracts. The bioactivities of S. compressa and E. arborea extracts were mainly related with their contents of three PGU phlorotannins and sulfated polysaccharides (e.g., fucoidan, laminarin, and alginate). These results suggest S. compressa and E. arborea are potential candidates for food products and nutraceutical and pharmaceutical preparations, and as additives for diabetes management. |
url |
http://dx.doi.org/10.1155/2019/3795160 |
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doaj-0a3cf9bf9d58431eb8f30d8026086de32020-11-25T01:07:48ZengHindawi LimitedBioMed Research International2314-61332314-61412019-01-01201910.1155/2019/37951603795160Nutraceutical Potential of Five Mexican Brown SeaweedsAna Rocío Múzquiz de la Garza0Mireya Tapia-Salazar1Maribel Maldonado-Muñiz2Julián de la Rosa-Millán3Janet Alejandra Gutiérrez-Uribe4Liliana Santos-Zea5Bertha Alicia Barba-Dávila6Denis Ricque-Marie7Lucía Elizabeth Cruz-Suárez8Universidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Programa Maricultura, Ave. Universidad SN, Cd. Universitaria F-67, San Nicolás de los Garza, Nuevo León 66455, MexicoUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Programa Maricultura, Ave. Universidad SN, Cd. Universitaria F-67, San Nicolás de los Garza, Nuevo León 66455, MexicoUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Programa Maricultura, Ave. Universidad SN, Cd. Universitaria F-67, San Nicolás de los Garza, Nuevo León 66455, MexicoTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Av. Eugenio Garza Sada 2501 Sur, Monterrey, Nuevo León 64849, MexicoTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Av. Eugenio Garza Sada 2501 Sur, Monterrey, Nuevo León 64849, MexicoTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Av. Eugenio Garza Sada 2501 Sur, Monterrey, Nuevo León 64849, MexicoTecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Av. Eugenio Garza Sada 2501 Sur, Monterrey, Nuevo León 64849, MexicoUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Programa Maricultura, Ave. Universidad SN, Cd. Universitaria F-67, San Nicolás de los Garza, Nuevo León 66455, MexicoUniversidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Programa Maricultura, Ave. Universidad SN, Cd. Universitaria F-67, San Nicolás de los Garza, Nuevo León 66455, MexicoIn search of pharmaceutically active products to control type 2 diabetes, five brown seaweeds (Silvetia compressa, Cystoseira osmundacea, Ecklonia arborea, Pterygophora californica, and Egregia menziesii) from the Northwest Mexican Pacific coast were investigated. Proximate composition and total polyphenol content (TPC) as phloroglucinol equivalents (PGE) were determined for the five seaweed powders and their respective hydroethanolic (1 : 1) extracts. Extracts were screened for their radical scavenging activity (DPPH and ORAC) and glycosidase inhibitory activity. HPLC-DAD, HPLC-MS-TOF, and ATR-FT-IR methodologies were used to identify the most abundant phlorotannins and sulfated polysaccharides in the extracts. Hydroethanolic extracts contained minerals (17 to 59% of the dry matter), proteins (4 to 9%), ethanol-insoluble polysaccharides (5.4 to 53%), nitrogen-free extract (NFE) (24.4 to 70.1%), lipids (5 to 12%), and TPC (2.6 to 47.7 g PGE per 100 g dry extract). S. compressa and E. arborea dry extracts presented the lowest ash content (26 and 17%, respectively) and had some of the highest phenolic (47.7 and 15.2 g PGE per 100 g extract), NFE (57.3 and 70.1%), and soluble polysaccharide (19.7 and 53%) contents. S. compressa and E. arborea extracts had the highest antioxidant activity (IC50 DPPH 1.7 and 3.7 mg mL−1; ORAC 0.817 and 0.801 mmol Trolox equivalent/g extract) and the highest α-amylase and α-glucosidase inhibitory capacities (IC50 940 and 1152 μg mL−1 against α-amylase and 194 and 647 μg mL−1 against α-glucosidase). The most abundant phlorotannins identified in the extracts were phloretol, fucophloroethol, and two- and three-phloroglucinol unit (PGU) phlorotannins. Laminarin, fucoidan, and alginate were among the sulfated polysaccharides identified in the extracts. The bioactivities of S. compressa and E. arborea extracts were mainly related with their contents of three PGU phlorotannins and sulfated polysaccharides (e.g., fucoidan, laminarin, and alginate). These results suggest S. compressa and E. arborea are potential candidates for food products and nutraceutical and pharmaceutical preparations, and as additives for diabetes management.http://dx.doi.org/10.1155/2019/3795160 |