DHA Protects Hepatocytes from Oxidative Injury through GPR120/ERK-Mediated Mitophagy

DHA Protects Hepatocytes from Oxidative Injury through GPR120/ERK-Mediated Mitophagy

Oxidative stress occurs in a variety of clinical liver diseases and causes cellular damage and mitochondrial dysfunction. The clearance of damaged mitochondria by mitophagy may facilitate mitochondrial biogenesis and enhance cell survival. Although the supplementation of docosahexaenoic acid (DHA) h...

Full description

Bibliographic Details
Main Authors: Jinglong Chen, Danping Wang, Yibo Zong, Xiaojing Yang
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
liver injury
DHA
mitophagy
ERK1/2 signaling
Online Access:https://www.mdpi.com/1422-0067/22/11/5675

Internet

https://www.mdpi.com/1422-0067/22/11/5675

Similar Items