Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines

Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines

<p>Abstract</p> <p>Background</p> <p>The neuroinflammatory responses in the spinal cord following bone cancer development have been shown to play an important role in cancer-induced bone pain (CIBP). Lipoxins (LXs), endogenous lipoxygenase-derived eicosanoids, represent...

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Bibliographic Details
Main Authors: Hu Shan, Mao-Ying Qi-Liang, Wang Jun, Wang Zhi-Fu, Mi Wen-Li, Wang Xiao-Wei, Jiang Jian-Wei, Huang Ya-Lin, Wu Gen-Cheng, Wang Yan-Qing
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Neuroinflammation
Subjects:
Lipoxins
Aspirin-triggered-15-epi-lipoxinA4
Astrocytes
Neurons
Proinflammatory cytokines
Cancer-induced bone pain
Spinal cord
Rats
Online Access:http://www.jneuroinflammation.com/content/9/1/278

Internet

http://www.jneuroinflammation.com/content/9/1/278

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