Characteristic and Mechanism of Drug-Herb Interaction Between Acetylsalicylic Acid and Danhong Injection Mediated by Organic Anion Transporters

Characteristic and Mechanism of Drug-Herb Interaction Between Acetylsalicylic Acid and Danhong Injection Mediated by Organic Anion Transporters

The mixture of Salvia miltiorrhiza and Carthamus tinctorius (Danhong injection, DHI) is widely prescribed in China for the treatment of cardiovascular and cerebrovascular diseases. In most cases, DHI is used in combination with acetylsalicylic acid (aspirin, ASA). However, the interaction between DH...

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Bibliographic Details
Main Authors: Jianping Li, Jingbo Lu, Yin Peng, Xuejun Xu, Chenkai Chen, Ming Gao, Ling Lin, Jianming Guo, Jinao Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
organic anion transporter
drug interaction
acetylsalicylic acid (aspirin)
Danhong injection
salicylic acid
aristolochic acid
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.577012/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.577012/full

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