Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice

Cytoplasmic FMR1-interacting protein 2 (CYFIP2) is a key component of the WAVE regulatory complex (WRC) which regulates actin polymerization and branching in diverse cellular compartments. Recent whole exome sequencing studies identified de novo hotspot variants in CYFIP2 from patients with early-on...

Full description

Bibliographic Details
Main Authors: Yinhua Zhang, Hyojin Kang, Yeunkum Lee, Yoonhee Kim, Bokyoung Lee, Jin Yong Kim, Chunmei Jin, Shinhyun Kim, Hyun Kim, Kihoon Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Cyfip2-null mice
Embryo
body size
postnatal lethality
extracellular matrix
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00482/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00482/full

Similar Items