Laquinimod attenuates inflammation by modulating macrophage functions in traumatic brain injury mouse model

Laquinimod attenuates inflammation by modulating macrophage functions in traumatic brain injury mouse model

Abstract Background Traumatic brain injury (TBI) is a critical public health and socio-economic problem worldwide. A growing body of evidence supports the involvement of inflammatory events in TBI. It has been reported that resident microglia and infiltrating monocytes promote an inflammatory reacti...

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Bibliographic Details
Main Authors: Atsuko Katsumoto, Aline S. Miranda, Oleg Butovsky, Antônio L. Teixeira, Richard M. Ransohoff, Bruce T. Lamb
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Neuroinflammation
Subjects:
Laquinimod
Microglia
Peripherally derived monocytes
Traumatic brain injury
Online Access:http://link.springer.com/article/10.1186/s12974-018-1075-y

Internet

http://link.springer.com/article/10.1186/s12974-018-1075-y

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