A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors

Summary Nestin-cre transgenic mice have been widely used to direct recombination to neural stem cells (NSCs) and intermediate neural progenitor cells (NPCs). Here we report that a readily utilized, and the only commercially available, Nestin-cre line is insufficient for directing recombination in ea...

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Bibliographic Details
Main Authors: Huixuan Liang, Simon Hippenmeyer, H. Troy Ghashghaei
Format: Article
Language:English
Published: The Company of Biologists 2012-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/1/12/1200