Signaling via ITGB1/FAK and microfilament rearrangement mediates the internalization of Leptospira interrogans in mouse J774A.1 macrophages

Signaling via ITGB1/FAK and microfilament rearrangement mediates the internalization of Leptospira interrogans in mouse J774A.1 macrophages

Leptospirosis caused by pathogenic Leptospira species is a worldwide zoonotic 2 infectious disease, but the mechanisms of leptospiral internalization remain poorly understood. Here, we report that mouse J774A.1 macrophages expressed integrin-subfamily proteins (ITGB1, ITGB2 and ITGB3). Anti...

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Bibliographic Details
Main Authors: Zhao Xin, Sun Ai-Hua, Ge Yu-Mei, Wang Huan, Yan Jie
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2015-01-01
Series:Archives of Biological Sciences
Subjects:
Leptospira interrogans
mouse macrophage cell
internalization
signaling
cytoskeletal rearrangement
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2015/0354-46641400005Z.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2015/0354-46641400005Z.pdf

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