The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.

<h4>Background</h4>The enzyme indoleamine 2,3-dioxygenase (IDO) exerts an well established immunosuppressive function in cancer. IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it promotes the establishment of periphera...

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Main Authors: Rikke Baek Sørensen, Linda Berge-Hansen, Niels Junker, Christina Aaen Hansen, Sine Reker Hadrup, Ton N M Schumacher, Inge Marie Svane, Jürgen C Becker, Per thor Straten, Mads Hald Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19738905/?tool=EBI