Identification of genetic factors underlying persistent pulmonary hypertension of newborns in a cohort of Chinese neonates

Identification of genetic factors underlying persistent pulmonary hypertension of newborns in a cohort of Chinese neonates

Abstract Background Persistent pulmonary hypertension of the newborn (PPHN) is a severe clinical problem among neonatal intensive care unit (NICU) patients. The genetic pathogenesis of PPHN is unclear. Only a few genetic polymorphisms have been identified in infants with PPHN. Our study aimed to inv...

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Bibliographic Details
Main Authors: Xu Liu, Mei Mei, Xiang Chen, Yulan Lu, Xinran Dong, Liyuan Hu, Xiaojing Hu, Guoqiang Cheng, Yun Cao, Lin Yang, Wenhao Zhou
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Respiratory Research
Subjects:
Persistent pulmonary hypertension of the newborn
Exome sequencing
Chinese
PAH genes
Genetic polymorphisms
Early diagnosis
Online Access:http://link.springer.com/article/10.1186/s12931-019-1148-1

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http://link.springer.com/article/10.1186/s12931-019-1148-1

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