Pyrosequencing, a method approved to detect the two major EGFR mutations for anti EGFR therapy in NSCLC

<p>Abstract</p> <p>Background</p> <p>Epidermal Growth Factor Receptor (EGFR) mutations, especially in-frame deletions in exon 19 (ΔLRE) and a point mutation in exon 21 (L858R) predict gefitinib sensitivity in patients with non-small cell lung cancer. Several methods are...

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Bibliographic Details
Main Authors: Richard Marie-Jeanne, Dufort Sandrine, Lantuejoul Sylvie, de Fraipont Florence
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/57