Pyrosequencing, a method approved to detect the two major EGFR mutations for anti EGFR therapy in NSCLC
<p>Abstract</p> <p>Background</p> <p>Epidermal Growth Factor Receptor (EGFR) mutations, especially in-frame deletions in exon 19 (ΔLRE) and a point mutation in exon 21 (L858R) predict gefitinib sensitivity in patients with non-small cell lung cancer. Several methods are...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-05-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Online Access: | http://www.jeccr.com/content/30/1/57 |