Altered Polarization, Morphology, and Impaired Innate Immunity Germane to Resident Peritoneal Macrophages in Mice with Long-Term Type 2 Diabetes

Type 2 diabetes (T2D) is associated with perturbed innate immunity. Macrophages, bridging innate immunity and metabolic disturbances, play important roles in controlling immune homeostasis. However, the effect of long-term diabetic milieu (DM) on the functions and phenotypes of macrophages is still...

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Bibliographic Details
Main Authors: Hui-Fang Liu, Hui-Jie Zhang, Qi-Xian Hu, Xiao-Yan Liu, Zhi-Quan Wang, Jia-Yan Fan, Ming Zhan, Feng-Ling Chen
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/867023