Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry

Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry

Canonical inflammasome activation is a tightly regulated process that has been implicated in a broad spectrum of inflammatory disorders. Inflammasome formation requires assembly of a cytosolic sensor protein with the adapter, ASC (apoptosis-associated speck-like protein containing a caspase activati...

Full description

Bibliographic Details
Main Authors: Silvia Lucena Lage, Venina Marcela Dominical, Chun-Shu Wong, Irini Sereti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
inflammasome
ASC speck
multispectral imaging flow cytometry (MIFC)
monocytes
caspase-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01284/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01284/full

Similar Items