Increasing the Efficacy of Oncolytic Adenovirus Vectors

Oncolytic adenovirus (Ad) vectors present a new modality to treat cancer. These vectors attack tumors via replicating in and killing cancer cells. Upon completion of the vector replication cycle, the infected tumor cell lyses and releases progeny virions that are capable of infecting neighboring tum...

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Bibliographic Details
Main Authors: William S. M. Wold, Karoly Toth
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/2/9/1844/