Single strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.

Single strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.

The hepatitis C virus (HCV) culture system has enabled us to clarify the HCV life cycle and essential host factors for propagation. However, the virus production level of wild-type JFH-1 (JFH-1/wt) is limited, and this leads to difficulties in performing experiments that require higher viral concent...

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Bibliographic Details
Main Authors: Nao Sugiyama, Asako Murayama, Ryosuke Suzuki, Noriyuki Watanabe, Masaaki Shiina, T Jake Liang, Takaji Wakita, Takanobu Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4029950?pdf=render

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http://europepmc.org/articles/PMC4029950?pdf=render

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