Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice

Abstract Objective This study was aimed to measure the effects of a high-fat diet and metformin on placental mechanistic target of rapamycin (mTOR) signaling in mice. Study Design Pregnant friend virus B (FVB)-strain mice were allocated on embryonic day (e) 0.5 to one of fo...

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Bibliographic Details
Main Authors: Matthew R. Grace, Sarah K. Dotters-Katz, Chunxiao Zhou, Tracy Manuck, Kim Boggess, Victoria Bae-Jump
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2019-04-01
Series:American Journal of Perinatology Reports
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1683362