Cardiac-Specific Overexpression of ERRγ in Mice Induces Severe Heart Dysfunction and Early Lethality

Cardiac-Specific Overexpression of ERRγ in Mice Induces Severe Heart Dysfunction and Early Lethality

Proper cardiac function depends on the coordinated expression of multiple gene networks related to fuel utilization and mitochondrial ATP production, heart contraction, and ion transport. Key transcriptional regulators that regulate these gene networks have been identified. Among them, estrogen-rela...

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Bibliographic Details
Main Authors: Jaime Lasheras, Rosario Pardo, Marc Velilla, Marcos Poncelas, Núria Salvatella, Rafael Simó, Marisol Ruiz-Meana, Mònica Zamora, Josep A. Villena
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
cardiac dysfunction
estrogen-related receptors
transgenic mice
Online Access:https://www.mdpi.com/1422-0067/22/15/8047

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https://www.mdpi.com/1422-0067/22/15/8047

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