Targeting Echinococcus multilocularis stem cells by inhibition of the Polo-like kinase EmPlk1.

Alveolar echinococcosis (AE) is a life-threatening disease caused by larvae of the fox-tapeworm Echinococcus multilocularis. Crucial to AE pathology is continuous infiltrative growth of the parasite's metacestode stage, which is driven by a population of somatic stem cells, called germinative c...

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Bibliographic Details
Main Authors: Andreas Schubert, Uriel Koziol, Katia Cailliau, Mathieu Vanderstraete, Colette Dissous, Klaus Brehm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4046951?pdf=render