Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Leprdb/db mice

Introduction Diabetic nephropathy (DN) develops in about 40% of patients with type 2 diabetes and remains the leading cause of end-stage renal disease. The mechanisms of DN remain to be elucidated. Oxidative stress is thought to be involved in the development of DN but antioxidant therapy has produc...

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Bibliographic Details
Main Authors: Tingting Yan, Sanqiao Yao, Weidong Wu, Yingzheng Zhao, Cheng Xiong, Meiyu Chang, Qiyu Gao, Xianwen Yi, Guangcui Xu
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/9/1/e002260.full