Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Leprdb/db mice
Introduction Diabetic nephropathy (DN) develops in about 40% of patients with type 2 diabetes and remains the leading cause of end-stage renal disease. The mechanisms of DN remain to be elucidated. Oxidative stress is thought to be involved in the development of DN but antioxidant therapy has produc...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-08-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/9/1/e002260.full |