Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions.

Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions.

Copy-number variations (CNV), loss of heterozygosity (LOH), and uniparental disomy (UPD) are large genomic aberrations leading to many common inherited diseases, cancers, and other complex diseases. An integrated tool to identify these aberrations is essential in understanding diseases and in design...

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Bibliographic Details
Main Authors: Wei Li, Yingying Xia, Chongzhi Wang, Y Tom Tang, Wenying Guo, Jinliang Li, Xia Zhao, Yepeng Sun, Juan Hu, Hefu Zhen, Xiandong Zhang, Chao Chen, Yujian Shi, Lin Li, Hongzhi Cao, Hongli Du, Jian Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4412667?pdf=render

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http://europepmc.org/articles/PMC4412667?pdf=render

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