Microglial KCa3.1 Channels as a Potential Therapeutic Target for Alzheimer’s Disease

There exists an urgent need for new target discovery to treat Alzheimer’s disease (AD); however, recent clinical trials based on anti-Aβ and anti-inflammatory strategies have yielded disappointing results. To expedite new drug discovery, we propose reposition targets which have been previously pursu...

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Bibliographic Details
Main Authors: Izumi Maezawa, David Paul Jenkins, Benjamin E. Jin, Heike Wulff
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2012/868972