Evaluation of the prognostic value of IFN-gamma release assay and tuberculin skin test in household contacts of infectious tuberculosis cases in Senegal.

Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, particularly in endemic countries, but is hampered by the difficulty to diagnose latent TB infection (LTBI), classically assessed through response to the Tuberculin Skin Test (TST). Interferon-gamma rel...

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Main Authors: Christian Lienhardt, Katherine Fielding, Abdoul A Hane, Aliou Niang, Cheikh T Ndao, Farba Karam, Helen Fletcher, Fatou Mbow, Jules-François Gomis, Raymond Diadhiou, Maxime Toupane, Tandakha Dieye, Souleymane Mboup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2865542?pdf=render