Autoregulation of yeast ribosomal proteins discovered by efficient search for feedback regulation

Here, the authors screen for feedback regulation of ribosomal proteins by overexpressing a non- regulatable version of a gene and observing its effects on the expression of the GFP-fused version. They find that 30% show at least a 3-fold reduction in expression and two genes show a 10-fold reduction...

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Bibliographic Details
Main Authors: Basab Roy, David Granas, Fredrick Bragg, Jonathan A. Y. Cher, Michael A. White, Gary D. Stormo
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01494-z