miR-618: possible control over TIMP-1 and its expression in localized prostate cancer

Abstract Background The imbalance between the action of the tissue inhibitors of matrix metalloproteinases (TIMPs) and the matrix metalloproteinases (MMPs) is one component of metastasis physiology. TIMP-1 overrides MMP-9 activity in cancer and might be regulated by miR-618. The aims of this study w...

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Main Authors: Renato F. Ivanovic, Nayara I. Viana, Denis R. Morais, Caio Moura, Iran A. Silva, Katia R. Leite, José Pontes-Junior, William C. Nahas, Miguel Srougi, Sabrina T. Reis
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4930-4