Human cartilaginous endplate degeneration is induced by calcium and the extracellular calcium-sensing receptor in the intervertebral disc

Human cartilaginous endplate degeneration is induced by calcium and the extracellular calcium-sensing receptor in the intervertebral disc

The cartilaginous endplates (CEPs) are thin layers of hyaline cartilage found adjacent to intervertebral discs (IVDs). In addition to providing structural support, CEPs regulate nutrient and metabolic exchange in the disc. In IVD pathogenesis, CEP undergoes degeneration and calcification, compromisi...

Full description

Bibliographic Details
Main Authors: MP Grant, LM Epure, R Bokhari, P Roughley, J Antoniou, F Mwale
Format: Article
Language:English
Published: AO Research Institute Davos 2016-07-01
Series:European Cells & Materials
Subjects:
Intervertebral disc
degeneration
cartilaginous endplate
calcification
calcium
extracellular calcium-sensing receptor
disc nutrition
Online Access:http://www.ecmjournal.org/papers/vol032/pdf/v032a09.pdf

Internet

http://www.ecmjournal.org/papers/vol032/pdf/v032a09.pdf

Similar Items