The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

The innate immune response plays a critical role in the host defense against invading pathogens, and TLR2, a member of the Toll-like receptor (TLR) family, has been implicated in the immune response and initiation of inflammatory cytokine secretion against several human viruses. Previous studies hav...

Full description

Bibliographic Details
Main Authors: Mingsheng Cai, Meili Li, Kezhen Wang, Shuai Wang, Qiong Lu, Jinghua Yan, Karen L Mossman, Rongtuan Lin, Chunfu Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557241?pdf=render

Internet

http://europepmc.org/articles/PMC3557241?pdf=render

Similar Items