Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

<h4>Objectives</h4>Nucleoside reverse transcriptase inhibitors (NRTIs) used in HIV antiretroviral therapy can inhibit human telomerase reverse transcriptase. We therefore investigated whether in utero or childhood exposure to NRTIs affects leukocyte telomere length (LTL), a marker of cel...

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Bibliographic Details
Main Authors: Hélène C F Côté, Hugo Soudeyns, Anona Thorne, Ariane Alimenti, Valérie Lamarre, Evelyn J Maan, Beheroze Sattha, Joel Singer, Normand Lapointe, Deborah M Money, John Forbes, CIHR Emerging Team in HIV therapy, aging (CARMA), Judy Wong, Ari Bitnun, Lindy Samson, Jason Brophy, David Burdge, Neora Pick, Julie van Schalkwyk, Julio Montaner, Marianne Harris, Patti Janssen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22815702/?tool=EBI