Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development

Schistosomiasis is a tropical disease caused by a flatworm trematode parasite that infects over 200 million people worldwide. Treatment and control of the disease rely on just one drug, praziquantel. The possibility of drug resistance coupled with praziquantel's variable efficacy encourages the...

Full description

Bibliographic Details
Main Authors: Nelly El-Sakkary, Steven Chen, Michelle R. Arkin, Conor R. Caffrey, Paula Ribeiro
Format: Article
Language:English
Published: The Company of Biologists 2018-07-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/7/dmm033563