Characterization and Establishment of an Immortalized Rabbit Melanocyte Cell Line Using the SV40 Large T Antigen

Characterization and Establishment of an Immortalized Rabbit Melanocyte Cell Line Using the SV40 Large T Antigen

Melanocytes (MCs) are specialized cells that synthesize melanin within the melanosome. Cultured MCs are useful in order to study their role in relation to pigmentation. However, MC isolation is laborious and the obtained cells have a limited culture time. In this study, we transformed lentivirus-med...

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Bibliographic Details
Main Authors: Yang Chen, Shuaishuai Hu, Manman Wang, Bohao Zhao, Naisu Yang, Jiali Li, Qiuran Chen, Ming Liu, Juan Zhou, Guolian Bao, Xinsheng Wu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
melanocytes
immortalization
sv40-lt
cell lines
malignant transformation
Online Access:https://www.mdpi.com/1422-0067/20/19/4874

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https://www.mdpi.com/1422-0067/20/19/4874

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