Bioinformatics analysis of the factors controlling type I IFN gene expression in autoimmune disease and virus-induced immunity

Bioinformatics analysis of the factors controlling type I IFN gene expression in autoimmune disease and virus-induced immunity

Patients with systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) display increased levels of type I IFN-induced genes. Plasmacytoid dendritic cells (PDCs) are natural interferon producing cells and considered to be a primary source of IFN-α in these two diseases. Diffe...

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Bibliographic Details
Main Authors: Di eFeng, Betsy eBarnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Transcription, Genetic
bioinformatics
Transcriptional regulation
Type I Interferons
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00291/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00291/full

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