The miR-1185-2-3p—GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1

The miR-1185-2-3p—GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1

Abstract Background Phosphatidylinositol-4-phosphate-binding protein GOLPH3L is overexpressed in human ductal carcinoma of the breast, and its expression levels correlate with the prognosis of breast cancer patients. However, the roles of GOLPH3L in breast tumorigenesis remain unclear. Methods We as...

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Bibliographic Details
Main Authors: Youqin Xu, Wancheng Chen, Jing Liang, Xiaoqi Zeng, Kaiyuan Ji, Jianlong Zhou, Shijun Liao, Jiexian Wu, Kongyang Xing, Zilong He, Yang Yang, Qianzhen Liu, Pingyi Zhu, Yuchang Liu, Li Li, Minfeng Liu, Wenxiao Chen, Wenhua Huang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Tumorigenesis
Glucose metabolism
Glycosylation
miRNA
p53-induced transcription
Online Access:https://doi.org/10.1186/s13046-020-01767-9

Internet

https://doi.org/10.1186/s13046-020-01767-9

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