A genome-wide association analysis reveals a potential role for recombination in the evolution of antimicrobial resistance in Burkholderia multivorans.

Cystic fibrosis (CF) lung infections caused by members of the Burkholderia cepacia complex, such as Burkholderia multivorans, are associated with high rates of mortality and morbidity. We performed a population genomics study of 111 B. multivorans sputum isolates from one CF patient through three st...

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Bibliographic Details
Main Authors: Julio Diaz Caballero, Shawn T Clark, Pauline W Wang, Sylva L Donaldson, Bryan Coburn, D Elizabeth Tullis, Yvonne C W Yau, Valerie J Waters, David M Hwang, David S Guttman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007453