Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

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PURPOSE: The provirus integration site for Moloney murine leukemia virus 1 (Pim-1) kinase is overexpressed in various tumors and has been linked to poor prognosis. Its role as proto-oncogene is based on several Pim-1 target proteins involved in pivotal cellular processes. Here, we explore the funct...

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Bibliographic Details
Main Authors:	Ulrike Weirauch, Nadine Beckmann, Maren Thomas, Arnold Grünweller, Kilian Huber, Franz Bracher, Roland K. Hartmann, Achim Aigner
Format:	Article
Language:	English
Published:	Elsevier 2013-07-01
Series:	Neoplasia: An International Journal for Oncology Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558613800711

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