Methods for Arylethylation of Amines and Heteroarenes

by Franz Bracher
Published 2018-04-01

New Perspectives in the Chemistry of Marine Pyridoacridine Alkaloids

by Alois Plodek, Franz Bracher
Published 2016-01-01

Pharmacokinetic Enhancers (Boosters)—Escort for Drugs against Degrading Enzymes and Beyond

by Jürgen Krauß, Franz Bracher
Published 2018-09-01

A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines

by Benedikt C. Melzer, Franz Bracher
Published 2017-08-01

Functionalization of 4-bromobenzo[c][2,7]naphthyridine via regioselective direct ring metalation. A novel approach to analogues of pyridoacridine alkaloids

by Benedikt C. Melzer, Alois Plodek, Franz Bracher
Published 2019-09-01

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines – a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinolin...

by Benedikt C. Melzer, Jan G. Felber, Franz Bracher
Published 2018-01-01

Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids

by Jürgen Krauß, Monika Klimt, Markus Luber, Peter Mayer, Franz Bracher
Published 2019-09-01

Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.

by Katharina Rüben, Anne Wurzlbauer, Agnes Walte, Wolfgang Sippl, Franz Bracher, Walter Becker
Published 2015-01-01

Inhibition of Phytosterol Biosynthesis by Azasterols

by Sylvain Darnet, Laetitia B B Martin, Pierre Mercier, Franz Bracher, Philippe Geoffroy, Hubert Schaller
Published 2020-03-01

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol

by Julia Junker, Isabelle Chong, Frits Kamp, Harald Steiner, Martin Giera, Christoph Müller, Franz Bracher
Published 2019-06-01

How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

by Anne Wurzlbauer, Katharina Rüben, Ece Gürdal, Apirat Chaikuad, Stefan Knapp, Wolfgang Sippl, Walter Becker, Franz Bracher
Published 2020-12-01

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

by Ulrike Weirauch, Nadine Beckmann, Maren Thomas, Arnold Grünweller, Kilian Huber, Franz Bracher, Roland K. Hartmann, Achim Aigner
Published 2013-07-01

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

by Ulrike Weirauch, Nadine Beckmann, Maren Thomas, Arnold Grünweller, Kilian Huber, Franz Bracher, Roland K. Hartmann, Achim Aigner
Published 2013-07-01

Schistosoma mansoni Sirtuins: characterization and potential as chemotherapeutic targets.

by Julien Lancelot, Stéphanie Caby, Florence Dubois-Abdesselem, Mathieu Vanderstraete, Jacques Trolet, Guilherme Oliveira, Franz Bracher, Manfred Jung, Raymond J Pierce
Published 2013-01-01

Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion.

by Daniela Mailänder-Sánchez, Christina Braunsdorf, Christian Grumaz, Christoph Müller, Stefan Lorenz, Philip Stevens, Jeanette Wagener, Betty Hebecker, Bernhard Hube, Franz Bracher, Kai Sohn, Martin Schaller
Published 2017-01-01

Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro[S]

by Alberto Canfrán-Duque, María E. Casado, Óscar Pastor, Jana Sánchez-Wandelmer, Gema de la Peña, Milagros Lerma, Paloma Mariscal, Franz Bracher, Miguel A. Lasunción, Rebeca Busto
Published 2013-02-01

Correction: Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.

by Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, Paul D Carr, Bharat Rash, Javier Capilla, Christoph Müller, Franz Bracher, Paul Bowyer, Hubertus Haas, Axel A Brakhage, Michael J Bromley
Published 2016-12-01

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex.

by Fabio Gsaller, Peter Hortschansky, Takanori Furukawa, Paul D Carr, Bharat Rash, Javier Capilla, Christoph Müller, Franz Bracher, Paul Bowyer, Hubertus Haas, Axel A Brakhage, Michael J Bromley
Published 2016-07-01

Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors

by Philipp Rühl, Anna Scotto Rosato, Nicole Urban, Susanne Gerndt, Rachel Tang, Carla Abrahamian, Charlotte Leser, Jiansong Sheng, Archana Jha, Günter Vollmer, Michael Schaefer, Franz Bracher, Christian Grimm
Published 2021-04-01

Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission.

by Selina Kern, Shruti Agarwal, Kilian Huber, André P Gehring, Benjamin Strödke, Christine C Wirth, Thomas Brügl, Liliane Onambele Abodo, Thomas Dandekar, Christian Doerig, Rainer Fischer, Andrew B Tobin, Mahmood M Alam, Franz Bracher, Gabriele Pradel
Published 2014-01-01