Druggable Nucleolin Identifies Breast Tumours Associated with Poor Prognosis That Exhibit Different Biological Processes

Druggable Nucleolin Identifies Breast Tumours Associated with Poor Prognosis That Exhibit Different Biological Processes

Background: Nucleolin (NCL) is a multifunctional protein with oncogenic properties. Anti-NCL drugs show strong cytotoxic effects, including in triple-negative breast cancer (TNBC) models, and are currently being evaluated in phase II clinical trials. However, few studies have investigated the clinic...

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Bibliographic Details
Main Authors: Flora Nguyen Van Long, Audrey Lardy-Cleaud, Susan Bray, Sylvie Chabaud, Thierry Dubois, Alexandra Diot, Alastair M. Thompson, Jean-Christophe Bourdon, David Perol, Philippe Bouvet, Jean-Jacques Diaz, Virginie Marcel
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cancers
Subjects:
nucleolin
breast cancer
prognostic marker
triple-negative breast cancer
Online Access:http://www.mdpi.com/2072-6694/10/10/390

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http://www.mdpi.com/2072-6694/10/10/390

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