Aspirin-exacerbated respiratory disease (AERD): Current understanding of AERD

The characteristics in AERD are severe adult-onset asthma, eosinophilic rhinosinusitis with nasal polyposis, and CysLT overproduction. The cause of AERD have remained unclear, however the decrease in the production of PGE2 caused by the reduction in COX-2 activity is considered to main pathological...

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Bibliographic Details
Main Authors: Masami Taniguchi, Chihiro Mitsui, Hiroaki Hayashi, Emiko Ono, Keiichi Kajiwara, Haruhisa Mita, Kentaro Watai, Yosuke Kamide, Yuma Fukutomi, Kiyoshi Sekiya, Noritaka Higashi
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Allergology International
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893019300589