Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells

Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells

Abstract Background The regulatory role of long noncoding RNAs (lncRNAs) have been partially proved in embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Methods In the current study, we investigated mouse ESC (mESC) self-renewal, differentiation, and proliferation in vitro by k...

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Bibliographic Details
Main Authors: Jiajie Tu, Geng Tian, Hoi-Hung Cheung, Wei Wei, Tin-lap Lee
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
lncRNA
Gas5
mESCs
iPSCs
Self-renewal
Pluripotency
Online Access:http://link.springer.com/article/10.1186/s13287-018-0813-5

Internet

http://link.springer.com/article/10.1186/s13287-018-0813-5

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