Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy

<p>Abstract</p> <p>Recent investigation of Cullin 4 (CUL4) has ushered this class of multiprotein ubiquitin E3 ligases to center stage as critical regulators of diverse processes including cell cycle regulation, developmental patterning, DNA replication, DNA damage and repair, and...

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Bibliographic Details
Main Authors: Zhang Hui, Higa Leigh
Format: Article
Language:English
Published: BMC 2007-02-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/2/1/5