Serine Protease-Mediated Cutaneous Inflammation: Characterization of an Ex Vivo Skin Model for the Assessment of Dexamethasone-Loaded Core Multishell-Nanocarriers

Serine Protease-Mediated Cutaneous Inflammation: Characterization of an Ex Vivo Skin Model for the Assessment of Dexamethasone-Loaded Core Multishell-Nanocarriers

Standard experimental set-ups for the assessment of skin penetration are typically performed on skin explants with an intact skin barrier or after a partial mechanical or chemical perturbation of the <i>stratum corneum</i>, but they do not take into account biochemical changes. Among the...

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Bibliographic Details
Main Authors: Janna Frombach, Fiorenza Rancan, Katharina Kübrich, Fabian Schumacher, Michael Unbehauen, Ulrike Blume-Peytavi, Rainer Haag, Burkhard Kleuser, Robert Sabat, Kerstin Wolk, Annika Vogt
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
skin barrier
skin penetration
dermatotherapy
drug delivery
nanotechnology
core-multi shell nanostructure
Online Access:https://www.mdpi.com/1999-4923/12/9/862

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https://www.mdpi.com/1999-4923/12/9/862

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