Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses

Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses

Abstract Rare protein-truncating variants (PTVs) in PALB2 confer increased risk to breast cancer, but relatively few studies have reported the characteristics of tumours with PALB2 PTVs. In this study, we describe molecular characteristics of tumours with either germline or somatic alterations in PA...

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Bibliographic Details
Main Authors: Pei Sze Ng, Jia Wern Pan, Muhammad Mamduh Ahmad Zabidi, Pathmanathan Rajadurai, Cheng Har Yip, Oscar M. Reuda, Alison M. Dunning, Antonis C. Antoniou, Douglas F. Easton, Carlos Caldas, Suet-Feung Chin, Soo Hwang Teo
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00254-4

Internet

https://doi.org/10.1038/s41523-021-00254-4

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