Current Perspectives on High-Throughput Sequencing (HTS) for Adventitious Virus Detection: Upstream Sample Processing and Library Preparation

Current Perspectives on High-Throughput Sequencing (HTS) for Adventitious Virus Detection: Upstream Sample Processing and Library Preparation

A key step for broad viral detection using high-throughput sequencing (HTS) is optimizing the sample preparation strategy for extracting viral-specific nucleic acids since viral genomes are diverse: They can be single-stranded or double-stranded RNA or DNA, and can vary from a few thousand bases to...

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Bibliographic Details
Main Authors: Siemon H. Ng, Cassandra Braxton, Marc Eloit, Szi Fei Feng, Romain Fragnoud, Laurent Mallet, Edward T. Mee, Sarmitha Sathiamoorthy, Olivier Vandeputte, Arifa S. Khan
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Viruses
Subjects:
adventitious virus
virus detection
high-throughput sequencing
next-generation sequencing
sample preparation
biologics
Online Access:http://www.mdpi.com/1999-4915/10/10/566

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http://www.mdpi.com/1999-4915/10/10/566

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