Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery

Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery

Piroxicam (PX), a main member of non-steroidal anti-inflammatory drugs (NSAIDs), is mainly used orally, which causes side effects of the gastrointestinal tract. It also has systemic effects when administered intramuscularly. Intra-articular (IA) delivery and encapsulation of PX in biodegradable poly...

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Bibliographic Details
Main Authors: Azizeh Rahmani Del Bakhshayesh, Abolfazl Akbarzadeh, Alireza Alihemmati, Hamid Tayefi Nasrabadi, Azadeh Montaseri, Soodabeh Davaran, Ali Abedelahi
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
piroxicam
intra-articular administration
drug delivery
pcl nanoparticle
collagen
Online Access:http://dx.doi.org/10.1080/10717544.2020.1716881

Internet

http://dx.doi.org/10.1080/10717544.2020.1716881

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