The role of free endosomal epitopes in the mechanisms of amelioration and flares of rheumatoid arthritis-associated conditions: pregnancy and infective hepatitis

The role of free endosomal epitopes in the mechanisms of amelioration and flares of rheumatoid arthritis-associated conditions: pregnancy and infective hepatitis

Abstract Background It is known that rheumatoid symptoms improve in pregnancy and in patients who develop infective jaundice. The mechanism of amelioration might involve the direct interaction of free endosomal self-epitopes that are released by the cells of the involved organ with antigen binding s...

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Bibliographic Details
Main Authors: Innocenzo Caruso, Enzo Massimo Caruso, Salvatore Santandrea, Franco Montrone, Piercarlo Sarzi Puttini, Marco Cazzola
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Translational Medicine Communications
Subjects:
Longstanding synovial fluid
Endosomal autoantigen
Endogenous immunotherapy
Self-epitope-receptor microcomplexes
Ultrafiltrates
Primary and secondary
Online Access:http://link.springer.com/article/10.1186/s41231-018-0022-3

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http://link.springer.com/article/10.1186/s41231-018-0022-3

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